Abstract

INTRODUCTION

Measles mumps rubella vaccine is considered as a potential allergen in children with egg allergy and although it is suggested to administer the vaccine without any evaluation in egg allergic patients, due to the presence of reported cases of anaphylaxis during vaccination in the literature this issue causes distress to both families and doctors. In this study the frequency of reactions observed after MMR vaccination and the necessity of skin prick test in the patients followed up with egg allergy in our clinic were evaluated.

METHODS

In our study, 82 patients followed up with egg allergy diagnosis and administered MMR vaccine between September 2013 and May 2015 were included to retrospective cross-sectional study.

RESULTS

The average age was 8,34±7,1 months, 37.8% (n=31) of the cases female. According to their diagnostic distribution, 68.3% (n=56) had atopic dermatitis, 8.5% (n=7) urticaria/ angioedema, 18.3% (n=15) reactive airway disease, and 4.9% (n=4) evaluated as anaphylaxis. Skin prick test was administered to 21% (n=17) before MMR vaccination. A whole dose of vaccine was administered to all cases except in two cases with anaphylaxis diagnosis. There was no reaction observed after MMR vaccine administration in any of the cases.

DISCUSSION AND CONCLUSION

No reaction observed in any of egg allergy cases after MMR vaccination. Since we didn’t observed any different reaction in these patients from other children, we think that there is no obligation for administering MMR vaccines at the centers in which the other vaccines done, and no necessity to administer MMR vaccine with prick test or in divided doses.